ICD10 Chapter 2 Neoplasms (C00-D49)Chapter 2 Neoplasms (C00-D49)
This chapter contains the following blocks:
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
C15-C26 Malignant neoplasms of digestive organs
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
C40-C41 Malignant neoplasms of bone and articular cartilage
C43-C44 Melanoma and other malignant neoplasms of skin
C45-C49 Malignant neoplasms of mesothelial and soft tissue
C50 Malignant neoplasms of breast
C51-C58 Malignant neoplasms of female genital organs
C60-C63 Malignant neoplasms of male genital organs
C64-C68 Malignant neoplasms of urinary tract
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system C73-C75 Malignant neoplasms of thyroid and other endocrine glands
C7A Malignant neuroendocrine tumors
C7B Secondary neuroendocrine tumors
C76-C80 Malignant neoplasms of ill-defined, other secondary and unspecified sites
C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue
D00-D09 In situ neoplasms
D10-D36 Benign neoplasms, except benign neuroendocrine tumors
D3A Benign neuroendocrine tumors
D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
Neoplasms of unspecified behavior
Note: Functional activity
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from
Chapter 4 may be used, to identify functional activity associated with any neoplasm.
Morphology [Histology]
Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ,
benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
Primary malignant neoplasms overlapping site boundaries
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified
to the subcategory/code .8 (‘overlapping lesion’), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
Malignant neoplasm of ectopic tissue
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant
neoplasms are coded to pancreas, unspecified (C25.9).

  • C15-C26 Malignant neoplasm of esophagus, GI , Liver

    ICD-10-CM-tabular April 1 2023 C15 Malignant neoplasm of esophagus Use additional code to identify:alcohol abuse and dependence (F10.-) C15.3 Malignant neoplasm of upper third of esophagus C18 Malignant neoplasm of colon Excludes1: malignant carcinoid tumors of the colon (C7A.02-) C18.0 Malignant neoplasm of cecum Malignant neoplasm of ileocecal valve C18.8 Malignant neoplasm of overlapping sites […]

  • C00-C14 Malignant neoplasm of oral cavity ,lip ,oropharynx

    ICD-10-CM-tabular April 1 2023 Malignant neoplasms (C00-C96) Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue (C00-C75) Malignant neoplasms of lip, oral cavity and pharynx (C00-C14) C00 Malignant neoplasm of lip Use additional code to identify:alcohol abuse and dependence (F10.-) […]

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